Generally speaking, diuretic drugs commonly used in clinic mainly include the following aspects:
1、 Thiazide diuretics such as hydrochlorothiazide, which is a medium effect diuretic, mainly acts on the medullary loop of renal tubules, can inhibit the reabsorption of sodium and chloride ions and increase the excretion of potassium.
2、 Loop diuretics are long-acting diuretics, such as furosemide and diuretic acid. The main mechanism is to inhibit the reabsorption of sodium and chloride ions in the medullary loop. Diuretics have faster effect, higher curative effect and less toxic and side effects. They can be used for renal edema caused by various reasons.
3、 Potassium preserving diuretics, commonly used drugs such as spironolactone and aminophenanthroline. Spironolactone can antagonize solid ketone, inhibit the reabsorption of sodium in the collecting tube and reduce the excretion of potassium in urine. Aminophenanthroline can directly act on renal tubules to achieve the purpose of diuresis. Hyperkalemia will occur if such drugs are taken for a long time.